Factors Determining Immunological Response to Vaccination against Tick-Borne Encephalitis Virus in Older Individuals

Factors Determining Immunological Response to Vaccination against Tick-Borne Encephalitis Virus in Older Individuals

We performed a cross-sectional study including 533 individuals (median age 61) from the highly TBE endemic Åland Islands in the archipelago between Sweden and Finland. Blood samples, questionnaires and vaccination records were obtained from all study participants. The aim was to investigate if there was any association between TBEV antibody titer and 12 health-related factors. Measurement of TB...

Factors associated with seroimmunity against tick borne encephalitis virus 10 years after booster vaccination.

In a sample of originally 430 healthy adults (18-84 years of age) with documented basic and booster immunization against tick borne encephalitis, cumulative seroprotection rates 8 (n=178) and 10 years (n=183) after the last booster dose were 86.8% and 77.3% according to the neutralization test, respectively. In subjects aged 50 years and older, antibody titers were significantly lower compared ...

Tick-borne Encephalitis Virus

T encephalitis (TBE), which is caused by tickborne encephalitis virus (TBEV), is a potentially fatal disease of the central nervous system, mainly in humans, but also in monkeys, dogs (1), and horses. Ruminants such as goats, sheep, and cattle are considered to be sporadically infected subclinically. However, they might be the source of disease in humans who consume nonpasteurized milk and milk...

Document on Vaccines and Vaccination against Tick - borne Encephalitis ( TBE ) *

Field effectiveness of vaccination against tick-borne encephalitis.

Tick-borne encephalitis (TBE) is a vaccine-preventable disease caused by a flavivirus (TBE virus) that is endemic in many European countries and large parts of Central and Eastern Asia. In Europe, highly purified formalin-inactivated whole virus vaccines are in widespread use, but the vaccination coverage differs significantly between countries with TBE endemicity. Austria presents an exception...